The only reason to use a GUI is if you need to do intensive graphics or high performance real time visualization. They all use html+css for the presentation which allow you to style your pages much better than a GUI ever could.

Most frameworks today build interfaces from you from data, handle all concurrency, come with database and database abstraction layer. When you develop a web app you typically use a framework. you see lots of GUI apps that freeze because of poor concurrency (this is not a limitation of the GUI but a complexity of the underlying programming model). 2) GUI's use system sockets why web apps use Internet sockets, which means the latter allows you (if you so choose) to run the computation and the presentation on separate machines 3) web apps handle concurrency better and therefore multiple users. The differences are that 1) GUI uses a limited set of proprietary controls vs a web app which uses the browser controls which can be extended using multiple JS libraries. A GUI has a very similar similar structure to a web app because both need to handle concurrency (the gui events and the computation). A web app can run on localhost and be accessible only to the current user.

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Problem Solving with Algorithms and Data Structures.

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